I blogged my desire of an Indian winning a Nobel in the Sciences just yesterday (here) and just now received the news that Venkatraman Ramakrishnan has won this years Nobel for Chemistry. (see here) He shares it with two others - Thomas A. Steiz and Ada E. Yonath.
Now if only all my desires were fulfilled this rapidly!!
PS: I am not that hung upon "achieved it in India". So what if he works in the US?